AT-406 HCl ( —— )

Catalog No. M17137 CAS No. 1071992-57-8

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Product Name

AT-406 HCl
Note

Research use only, not for human use.
Brief Description

AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP).
Description

AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Apoptosis protein
Research Area

——
Indication

——

CAS Number

1071992-57-8
Formula Weight

598.19
Molecular Formula

C32H44ClN5O4
Purity

98%
Solubility

——
SMILES

N12[C@@H](CCN(C[C@@H](C1=O)NC(=O)[C@H](C)NC)C(=O)CC(C)C)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
Chemical Name

——

1. Melissa KB, et al. Y Biol Ther. 2012 Jul 1; 13(9): 804–811.

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